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Continuous Flow Technology Lab Services | TCG GreenChem

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The Continuous Flow Technology Lab (CFL) compliments ARDEL by creating unique opportunities to convert batch processing into continuous flow processes. As documented below, continuous flow chemistry is a disruptive technology and has many attributes: Reduce Footprint/Capital to Manufacture SM, RSM, and API Able to Do Hazardous Chemical Reactions in a Safe Operating Mode Able to Create Economical Low Temperature Reactions Because Cooling a Smaller Reactor Volume (15 Ml Reactor Volume vs. 4,000L Reactor) Reduce Time by Doing Processes at Higher Temperatures or Pressures Safely Capture Unique IP for Client Increase Productivity and Reduce Cost for Processes

Advanced Process Research & Development | High-end Facilities

Process Research & Development The focus of the company is on helping the biotech, pharmaceutical, generic, and chemical industry to develop scalable, practical, robust and economically feasible syntheses for supporting small molecule business. Develop cost-efficient, green, and sustainable manufacturing processes for intermediates and APIs Identification of polymorphic forms and development of robust crystallization Engineering novel solutions for complex synthetic processes Accelerate development of phase appropriate synthetic processes for APIs Remove hazardous, dangerous, and expensive chemistry Rapid Scale-up to Pre-clinical and IND Toxicology Studies Impurities and Intermediates Preparation Supply Chain Management and Starting Material Preparation HAZOP and Process R&D Evaluate Key Parameters for Vessel Design (MOC, Agitation, etc.) New Route Scouting and Process Development Raw Materials Selection Scalability Assessment Solution Stability and Hold Time Studies